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Table 1 Summary of published buprenorphine low dose induction protocols

From: Low dose IV buprenorphine inductions for patients with opioid use disorder and concurrent pain: a retrospective case series

 

Total daily buprenorphine dosage (mg)

Day 1

Day 2

Day 3

Day 4

Day 5

Bernes method

 

0.2 SL

0.2 SL

2.8 SL

4.5 SL

5 SL

Hammig (2016)

 

0.2 SL

0.8 SL

1.2 SL

1.8 SL

2.0 SL

Terasaki (2019)

 

0.5 SL

1.0 SL

2.0 SL

4.0 SL

8.0 SL

Crane (2020)

 

0.1 IV

1.1 IV

1.2 IV

1.6 IV

1.5 IV

Teck (2021)

 

0.4 SL

0.4 SL

0.8 SL

1.2 SL

1.6 SL

Jablonski (2022)

 

1.0 IV

1.8 IV

4.0 SL

–

–

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Addiction Science & Clinical Practice

ISSN: 1940-0640