Table 1 Inpatient multimodal analgesic regimen in a 41-year-old male with an opioid withdrawal-like acute phase reaction from intravenous zoledronate
From: An acute phase reaction from zoledronate mimicking symptoms seen in opioid withdrawal: a case report
Day 1 (prior to symptom onset) *Zoledronate Infusion Given | Day 2 (symptom onset) | Day 3 (symptom resolution) |
|---|---|---|
⋅ Discontinued intravenous hydromorphone 0.5 mg every 6 h as needed for breakthrough pain ⋅ Acetaminophen 975 mg every 8 h scheduled ⋅ Buprenorphine-Naloxone 2 mg twice daily ⋅ Oral hydromorphone 4 and 6 mg every 3 h as needed for moderate to severe pain ⋅ Cyclobenzaprine 5 mg 3 times daily ⋅ Gabapentin 600 mg 3 times daily ⋅ Naproxen 500 mg twice daily | ⋅ Acetaminophen 975 mg every 8 h scheduled ⋅ Buprenorphine-Naloxone 2 mg twice daily with plan to up titrate to minimum dose of 8 mg total daily dose prior to discharge ⋅ Oral hydromorphone 4 and 6 mg every 3 h as needed for moderate to severe pain ⋅ Cyclobenzaprine 5 mg 3 times daily ⋅ Gabapentin 600 mg 3 times daily ⋅ Naproxen 500 mg twice daily | ⋅ Same as Day 2 |