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Table 2 24-h opioid requirements by day in a 41-year-old male with a history of opioid use disorder complicated by significant infection hospitalized for treatment and surgical intervention

From: An acute phase reaction from zoledronate mimicking symptoms seen in opioid withdrawal: a case report

Days

24 Hour Opioid Requirement

Morphine Milligram Equivalents (MME)

Day 1 (prior to symptom onset)

Zoledronate Infusion Given

1. 36 mg oral hydromorphone

2. 0.5 mg intravenous hydromorphone

3. 4 mg sublingual buprenorphine-naloxone

146 MME

Day 2 (symptom onset)

1. 30 mg oral hydromorphone

2. 4 mg sublingual buprenorphine-naloxone

120 MME

Day 3 (symptom resolution)

1. 30 mg oral hydromorphone

2. 4 mg sublingual buprenorphine-naloxone

120 MME