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Table 2 Factors associated with 12 months retention of individuals enrolled in the Medication for Opioid Use Disorder programme in Kampala, Uganda(September 2020-July 2022)

From: Retention of people who inject drugs enrolled in a ‘medications for opioid use disorder’ (MOUD) programme in Uganda

Variables

Retention percentage (95%CI)

Unadjusted HR(95%CI)

Adjusted HR(95%CI)

Overall retention

55.6 (50.3–60.6)

  

Dose of methadone

   

Low (< 60 mg)

48.4(41.9–54.5)

1

1

High ( > = 60 mg)

71.8 ((61.8–79.6)

2.19(1.45–3.30)

2.1(1.41–3.22)

Age: 15-24yrs

57.4(44.3–68.5)

1

 

25-34yrs

50.3(42.6–57.6)

1.12(0.73–1.71)

 

Above35yrs

61.5(51.7–69.9)

0.88(0.54–1.43)

 

Sex Male

56.9(50.9–62.4)

1

 

Female

46.8(33.6–58.9)

0.71(0.48–1.05)

 

Distance: More or = 5Km

47.2(41.2–52.9)

1

1

Less than5Km

88.1(77.5–93.8)

6.01(2.95–12.26)

4.81(1.54-15.0)

Relocated close to MOUD clinic

   

NO

49.1 (43.2–54.7)

1

1

YES

88.7 (76.5–94.8)

6(2.65–13.58)

0.68(0.19–2.42)

Missed doses: None missed

63.7(55.9–70.5)

1

1

One/more doses

47.2(39.6–54.3)

0.69(0.49–0.95)

0.85(0.61–1.17)

History of Alcohol

   

NO/No response

58.1 (51.7–64)

1

 

YES

47.4(37.1–57.1)

0.75(0.53–1.03)

 

HIV serostatus

   

POSITIVE

56.7(37.3–72.1)

1

1

NEGATIVE/UNKNOWN

55(49.3–60.3)

0.99(0.57–1.77)

0.98(0.55–1.74)

Major Mental Health Illness

   

NO

56.1(50.2–61.6)

1

1

YES

50(36.1–62.4)

1.18(0.78–1.79)

1.1(0.71–1.7)

Housing -Stable

55.5(48.9–61.5)

1

 

Non-Stable

54.4(44.3–63.4)

0.93(0.66–1.3)

 

COWS Score

50(40.8–58.7)

1

 

MILD

   

MODERATE

60.3(52.5–67.3)

1.33(0.93–1.88)

 

SEVERE

42.8(21.9–62.3)

0.85(0.43–1.75)

 

Incarceration history

   

YES

40(16.5–62.8)

1

 

NO

55.7(48.6–62.2)

1.37(0.71–2.94)