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  1. Excessive alcohol consumption is a significant global health issue, often unaddressed in primary care. The 15-method, a three-step opportunistic screening and treatment tool premised on Motivational Interviewi...

    Authors: Peter Næsborg Schøler, Jens Søndergaard, Sanne Rasmussen, Kristina Hasselbalch Volke, Per Nilsen and Anette Søgaard Nielsen
    Citation: Addiction Science & Clinical Practice 2025 20:43
    Content type: Research Published on:

  2. Buprenorphine is a common partial opioid agonist treatment for opioid use disorder (OUD). Despite its efficacy, major challenges to induction include the significant time consumption and the difficult requirem...

    Authors: Pouya Azar, Jessica Machado, Jane J. Kim, James S. H. Wong, Mohammadali Nikoo and Victor W. Li
    Citation: Addiction Science & Clinical Practice 2025 20:42
    Content type: Case Report Published on:

  3. Every year about three million people die globally due to harmful alcohol use. The treatment gap remains high: only about 14% of individuals with problematic alcohol use access treatment. The implementation of...

    Authors: Elisabeth Petersén, Hanna Augustsson Öfverström, Magnus Johansson, Christopher Sundström and Anne H. Berman
    Citation: Addiction Science & Clinical Practice 2025 20:41
    Content type: Research Published on:

  4. Cocaine and methamphetamine use disorders (CcUD/MtUD) have serious public health, medical, and psychiatric consequences. Yet, there are no U.S. Food and Drug Administration (FDA) approved treatments available....

    Authors: Zahraa Atoui, Donald Egan, Manish Kumar Jha, Karen Hartwell, Russell Toll, Susan Sonne, Brenda Brunner-Jackson, Geetha Subramaniam, Jenna L. McCauley, Madhukar Trivedi and Kathleen Brady
    Citation: Addiction Science & Clinical Practice 2025 20:40
    Content type: Methodology Published on:

  5. Opioid use disorder often co-occurs with other mental health and substance use disorders. Identifying clusters of individuals receiving treatment for opioid use disorder based on co-diagnosed conditions, healt...

    Authors: Orrin D. Ware, Jamey J. Lister, Sarah E. Cooper, Andrew H. Kim, Holly H. Lister, N. Andrew Peterson, Stephen Fioravanti, Kristen Gilmore Powell, Stephanie C. Marcello and Bethany Joseph
    Citation: Addiction Science & Clinical Practice 2025 20:39
    Content type: Research Published on:

  6. Medications for opioid use disorder are evidence-based, guideline-recommended treatments. While buprenorphine can be prescribed in nonspecialized office-based settings, it is underutilized. Using a multifacete...

    Authors: Aline Lott, Anissa N. Danner, Carol A. Malte, Hope A. Salameh, Diana Bachowski, Adam J. Gordon, Hildi J. Hagedorn, Madeline C. Frost, Emily C. Williams, Andrew J. Saxon, Ryan S. Trim and Eric J. Hawkins
    Citation: Addiction Science & Clinical Practice 2025 20:38
    Content type: Research Published on:

  7. Programs that aim to increase access to substance use disorder (SUD) treatment in hospital-based settings have proliferated in recent years. These efforts include transitional opioid programs (TOPs), which nav...

    Authors: Zoe Lindenfeld, Berkeley Franz, Alden Yuanhong Lai, José A. Pagán, Cheyenne Fenstemaker, Cory E. Cronin and Ji Eun Chang
    Citation: Addiction Science & Clinical Practice 2025 20:37
    Content type: Research Published on:

  8. E-cigarette use (i.e., vaping) is prevalent among young adults in the U.S. Studies show that young adults who vape are more likely to initiate cigarette smoking than young adults who do not vape. Despite this,...

    Authors: Denise D. Tran, Jordan P. Davis, Keegan Buch, Adam M. Leventhal, Sarah W. Feldstein Ewing and Eric R. Pedersen
    Citation: Addiction Science & Clinical Practice 2025 20:36
    Content type: Study Protocol Published on:

  9. Longer duration of treatment with medication for opioid use disorder (MOUD) is associated with improved outcomes, but long-term retention remains a challenge. Research is needed to identify psychosocial interv...

    Authors: Emma N. Cleary, Angela L. Rollins, Alan B. McGuire, Laura J. Myers and Patrick D. Quinn
    Citation: Addiction Science & Clinical Practice 2025 20:35
    Content type: Research Published on:

  10. Cue exposure (CE) is used for relapse prevention as part of smoking cessation therapy to reduce the automatized response to smoking-related cues. Using CET in virtual reality (VR) is an approach to increase it...

    Authors: A. M. Kroczek, B. Schröder, D. Rosenbaum, A. Mühleck, J. Diemer, A. Mühlberger, A. C. Ehlis and A. Batra
    Citation: Addiction Science & Clinical Practice 2025 20:34
    Content type: Research Published on:

  11. In response to greater illicit fentanyl use, buprenorphine daily doses exceeding the FDA’s recommended target daily dose (16 mg) and maximum suggested daily dose (24 mg) may provide better outcomes, but little...

    Authors: Bradley D. Stein, Flora Sheng, Brendan K. Saloner, Adam J. Gordon and Jessica S. Merlin
    Citation: Addiction Science & Clinical Practice 2025 20:33
    Content type: Research Published on:

  12. Palliative care focuses on controlling symptoms and improving the patient’s quality of life. To achieve this, medications with addictive potential are often used. There have been various case reports of substa...

    Authors: Jannis Eersink, Julian Maul, Nils Heuser, Astrid Morin, Martin Gschnell and Christian Volberg
    Citation: Addiction Science & Clinical Practice 2025 20:32
    Content type: Research Published on:

  13. Detrimental smoking-related health outcomes warrant the investigation of novel smoking cessation interventions; the cessation program nuumi integrates digital behavioral therapy and an electronic cigarette (EC).

    Authors: Helen Schiek, Tobias Esch and Cosima Hoetger
    Citation: Addiction Science & Clinical Practice 2025 20:31
    Content type: Research Published on:

  14. Insomnia is a common condition experienced by many individuals with excessive alcohol use and alcohol use disorder, and the serotonin antagonist and reuptake inhibitor trazodone has emerged as a mainstay of tr...

    Authors: Jeffrey Pan, Jürgen Rehm and Evan Wood
    Citation: Addiction Science & Clinical Practice 2025 20:30
    Content type: Comment Published on:

  15. Authors: E. Jennifer Edelman, Oscar F. Rojas-Perez, Charla Nich, Joanne Corvino, Tami Frankforter, Derrick Gordon, Ayana Jordan, Manuel Paris, Jr, Melissa B. Weimer, Brian T. Yates, Emily C. Williams and Brian D. Kiluk
    Citation: Addiction Science & Clinical Practice 2025 20:29
    Content type: Correction Published on:

    The original article was published in Addiction Science & Clinical Practice 2023 18:55

  16. The Car, Relax, Alone, Forget, Friends, Trouble (CRAFFT) scale is a widely used screening tool for early identification of alcohol and other drug use, and assessing the risk of substance use disorders in adole...

    Authors: Hicham El Malki, Abdelfettah El-Ammari, Salma Ghofrane Moutawakkil, Samir Elgnaoui, Fatima El Houari, Karima El Rhazi and Btissame Zarrouq
    Citation: Addiction Science & Clinical Practice 2025 20:28
    Content type: Research Published on:

  17. Efforts to scale up overdose education and naloxone distribution (OEND), an evidence-based practice for reducing opioid overdose mortality, was a major focus of the HEALing Communities Study (HCS). The aim of ...

    Authors: Hannah K. Knudsen, Sandra Back-Haddix, Shaquita Andrews-Higgins, Michael Goetz, Olivia A. Davis, Douglas R. Oyler, Sharon L. Walsh and Patricia R. Freeman
    Citation: Addiction Science & Clinical Practice 2025 20:27
    Content type: Research Published on:

  18. An estimated 84,181 people died due to opioid overdose in 2022 alone [1]. Mobile technologies may offer an additional pathway to provide support to people seeking recovery from opioid use disorder (OUD). To this ...

    Authors: Alivia Williamson, Behnam Heydarshahi, Diadora Finley-Abboud, Lili Massac, Lindsay Jacobson, Naicha Christophe, Judeline Joseph, Allison Futter, Susanne S. Hoeppner and Bettina B. Hoeppner
    Citation: Addiction Science & Clinical Practice 2025 20:26
    Content type: Research Published on:

  19. Translating innovative research advancements into commercially viable medical interventions presents well-known challenges. However, there is limited understanding of how specific patient, clinical, social, an...

    Authors: Matthew P. Heshmatipour, Tyler M. Duvernay, Desislava Z. Hite, Eboo Versi, Michael P. Hite, David F. Reeser, Victor Prikhodko, Ariana M. Nelson, Bina Julian and Milton L. Greenberg
    Citation: Addiction Science & Clinical Practice 2025 20:25
    Content type: Research Published on:

  20. Authors: Kevin Y. Xu, Jennifer K. Bello, Joanna Buss, Hendrée E. Jones, Laura J. Bierut, Dustin Stwalley, Hannah S. Szlyk, Caitlin E. Martin, Jeannie C. Kelly, Ebony B. Carter, Elizabeth E. Krans and Richard A. Grucza
    Citation: Addiction Science & Clinical Practice 2025 20:24
    Content type: Correction Published on:

    The original article was published in Addiction Science & Clinical Practice 2025 20:1

  21. Conducting research within a carceral health care context offers a unique view into the nature of drug use among arrestees with potential to identify and prevent drug use consequences. The purpose of this stud...

    Authors: Joseph E. Schumacher, Abdullah Ahsan, Amber H. Simpler, Adam P. Natoli and Bradley J. Cain
    Citation: Addiction Science & Clinical Practice 2025 20:23
    Content type: Research Published on:

  22. Buprenorphine is an effective first-line treatment for opioid use disorder (OUD) that substantially reduces morbidity and mortality. For patients using illicitly-manufactured fentanyl (IMF), however, transitio...

    Authors: Beth E. Williams, Stephen A. Martin, Kim A. Hoffman, Mason D. Andrus, Elona Dellabough-Gormley and Bradley M. Buchheit
    Citation: Addiction Science & Clinical Practice 2025 20:22
    Content type: Research Published on:

  23. Deaths from opioid overdose have increased dramatically in the past decade. For individuals with opioid use disorder (OUD), agonist medications such as methadone and buprenorphine reduce opioid-related morbidi...

    Authors: Melissa Davoust, Angela R. Bazzi, Samantha Blakemore, Juliana Blodgett, Anna Cheng, Sarah Fielman, Kara M. Magane, Jacqueline Theisen, Richard Saitz, Alicia S. Ventura and Zoe M. Weinstein
    Citation: Addiction Science & Clinical Practice 2025 20:21
    Content type: Research Published on:

  25. Public health experts currently agree that heated tobacco products (HTPs) pose a significant health risk for their consumers. The same concentrations and speed of delivery of nicotine found for HTPs and conven...

    Authors: Feten Fekih-Romdhane, Rabih Hallit, Diana Malaeb, Fouad Sakr, Mariam Dabbous, Sahar Obeid and Souheil Hallit
    Citation: Addiction Science & Clinical Practice 2025 20:20
    Content type: Research Published on:

  26. Withdrawal prior to buprenorphine initiation may be intolerable or create barriers to therapy. We aim to update our previous systematic review on the efficacy and safety of buprenorphine initiation strategies ...

    Authors: Kathleen K. Adams, Kristin Waters and Diana M. Sobieraj
    Citation: Addiction Science & Clinical Practice 2025 20:19
    Content type: Review Published on:

  27. Addiction Medicine training in Canada has evolved substantially in the last few years with the establishment of accreditation standards and several new fellowship programs. The novelty of these formal training...

    Authors: Clara Lu, Kathryn Chan, Leslie Martin and Nadia Fairbairn
    Citation: Addiction Science & Clinical Practice 2025 20:18
    Content type: Research Published on:

  28. Little is known regarding predictors of outcome in treatment of alcohol dependence via the internet and in primary care. The aim of the present study was to investigate the role of socio-demographic and clinic...

    Authors: Karin Hyland, Danilo Romero, Sven Andreasson, Anders Hammarberg, Erik Hedman-Lagerlöf and Magnus Johansson
    Citation: Addiction Science & Clinical Practice 2025 20:17
    Content type: Research Published on:

  29. The availability of the fellowships of Alcoholics Anonymous and Narcotics Anonymous in community settings is extensive and patients admitted to treatment programs for substance use disorder may therefore have ...

    Authors: Marc Galanter, William L. White, Michael L. Dennis, Brooke Hunter, Lora Passetti and Dan Lustig
    Citation: Addiction Science & Clinical Practice 2025 20:16
    Content type: Research Published on:

  30. In South Africa, community-oriented primary care teams work to re-engage out-of-care people with HIV (PWH) in treatment, many of whom have substance use (SU) concerns. SU stigma is high among these teams, limi...

    Authors: Bronwyn Myers, Kristen S. Regenauer, Kim Johnson, Imani Brown, Alexandra L. Rose, Nonceba Ciya, Sibabalwe Ndamase, Yuche Jacobs, Morgan S. Anvari, Abigail Hines, Dwayne Dean, Rithika Baskar and Jessica F. Magidson
    Citation: Addiction Science & Clinical Practice 2025 20:15
    Content type: Research Published on:

  31. Individuals with opioid use disorder face barriers accessing first-line pharmacotherapy. Home delivery interventions have been shown to improve medication adherence for other chronic diseases, but the relation...

    Authors: Marlene C. Lira, Lauren E. Hendy, Alisha Liakas, Laura Turanchik, Clare Pritchard, Cynthia Jimes and M. Justin Coffey
    Citation: Addiction Science & Clinical Practice 2025 20:14
    Content type: Correspondence Published on:

  32. Given the opioid overdose crisis, surveillance of evolving opioid use patterns is critical to the effective deployment of mitigation strategies. The National Survey on Drug Use and Health (NSDUH) provided the ...

    Authors: Jarratt D. Pytell, Paul J. Christine, Katherine LeMasters, Karilynn M. Rockhill, Joshua C. Black, Richard C. Dart and Ingrid A. Binswanger
    Citation: Addiction Science & Clinical Practice 2025 20:13
    Content type: Research Published on:

  33. Posttraumatic stress disorder (PTSD) is highly comorbid with substance use disorders (SUDs), resulting in high prevalence of PTSD among individuals in residential SUD care. However, there is limited research o...

    Authors: Natalia Van Doren, Fang-Hsi Chang, Amanda Nguyen, Kevin R. McKenna, Derek D. Satre and Shannon Wiltsey-Stirman
    Citation: Addiction Science & Clinical Practice 2025 20:11
    Content type: Research Published on:

  34. The increase in opioid use disorder among young, nonurban people has fueled sharp rises in hepatitis C virus (HCV) infections. Innovative treatment models are needed that circumvent healthcare system barriers ...

    Authors: Kim Hoffman, Gillian Leichtling, Sarah Shin, Andrew Seaman, Tonhi Gailey, Hunter C. Spencer and P. Todd Korthuis
    Citation: Addiction Science & Clinical Practice 2025 20:10
    Content type: Research Published on:

  35. Unhealthy alcohol use, a spectrum of use inclusive of risky consumption and alcohol use disorder (AUD), is a leading cause of preventable death in the United States. Most people with unhealthy alcohol use do n...

    Authors: Kara M. Magane, Richard Saitz, Sarah Fielman, Marc R. LaRochelle, Christopher W. Shanahan, Christine A. Pace, Michael LaValley, Kaley Penington, Skylar Karzhevsky and Emily Hurstak
    Citation: Addiction Science & Clinical Practice 2025 20:9
    Content type: Study Protocol Published on:

  36. Buprenorphine (BUP) treatment has been successfully integrated into primary care and other general medical settings; however, potential BUP prescribers frequently report inadequate training and resources to pr...

    Authors: Mariya Masyukova, Benjamin T. Hayes, Teresa López-Castro and Aaron D. Fox
    Citation: Addiction Science & Clinical Practice 2025 20:8
    Content type: Research Published on:

  37. Medications for opioid use disorder (MOUD) are among the best tools available to combat the opioid epidemic. Yet, use of MOUD among people with opioid use disorder (OUD) remains low. Interventions to increase ...

    Authors: Nicholas C. Cardamone, Rebecca E. Stewart, Kyle M. Kampman and Steven C. Marcus
    Citation: Addiction Science & Clinical Practice 2025 20:7
    Content type: Research Published on:

  38. Initiation of buprenorphine for treatment of opioid use disorder (OUD) in acute care settings improves access and outcomes, however patients who use methamphetamine are less likely to link to ongoing treatment...

    Authors: Elenore P. Bhatraju, Devin N. Kennedy, Alexander J. Gojic, Matthew Iles-Shih, Joseph O. Merrill, Jeffrey H. Samet, Kevin A. Hallgren and Judith I. Tsui
    Citation: Addiction Science & Clinical Practice 2025 20:6
    Content type: Study Protocol Published on:

  39. Unhealthy alcohol use is an independent, modifiable risk factor for HIV, but limited research addresses alcohol use and HIV prevention synergistically. Groups that experience chronic stigma, discrimination, an...

    Authors: Olivia V. Fletcher, Kristine Beaver, Elizabeth J. Austin, Jenna van Draanen, E. Jennifer Edelman and Emily C. Williams
    Citation: Addiction Science & Clinical Practice 2025 20:5
    Content type: Research Published on:

  40. Women involved in the criminal legal system have elevated rates of opioid use disorder, which is treatable, and HIV, which is preventable with pre-exposure prophylaxis (PrEP). There are significant social and ...

    Authors: Jaimie P. Meyer, Stacey Brunson, Carolina R. Price, Morgan Mulrain, Julie Nguyen, Frederick L. Altice, Tassos C. Kyriakides, Karen Cropsey and Ellen Eaton
    Citation: Addiction Science & Clinical Practice 2025 20:4
    Content type: Study Protocol Published on:

  41. Opioid-related fatal overdoses are occurring at historically high levels and increasing each year. Accessible social and financial support are imperative to the initiation and success of treatment for Opioid U...

    Authors: Emily G. Hichborn, Owen B. Murray, Eilis I. Murphy, Tess E. Gallant, Sarah K. Moore, Bethany M. McLeman, John Saroyan, Anthony Folland, Megan Mitchell and Lisa A. Marsch
    Citation: Addiction Science & Clinical Practice 2025 20:3
    Content type: Research Published on:

  42. College students who are in recovery from substance use disorders face challenges related to abstaining from substance use, finding supportive social networks, and achieving their academic goals. These student...

    Authors: Lindsey M. Nichols, Tiffany B. Brown, Angela Allmendinger, Emily A. Hennessy and Emily E. Tanner-Smith
    Citation: Addiction Science & Clinical Practice 2025 20:2
    Content type: Research Published on:

  43. The postpartum period provides an opportunity for birthing people with opioid use disorder (OUD) to consider their future reproductive health goals. However, the relationship between the use of medication for ...

    Authors: Kevin Y. Xu, Jennifer K. Bello, Joanna Buss, Hendrée E. Jones, Laura J. Bierut, Dustin Stwalley, Hannah S. Szlyk, Caitlin E. Martin, Jeannie C. Kelly, Ebony B. Carter, Elizabeth E. Krans and Richard A. Grucza
    Citation: Addiction Science & Clinical Practice 2025 20:1
    Content type: Research Published on:

    The Correction to this article has been published in Addiction Science & Clinical Practice 2025 20:24

  44. Family physicians (FPs) are the first point of contact for people who smoke who are seeking to quit smoking in Türkiye. We aimed to explore Turkish FPs knowledge, attitudes and perceptions of e-cigarettes as s...

    Authors: Melis Selamoglu, Ayse Emel Onal, Bircan Erbas, Selma Karabey, Meryem Merve Oren, Mahmut Talha Ucar and Chris Barton
    Citation: Addiction Science & Clinical Practice 2024 19:99
    Content type: Research Published on:

  45. The American Society of Addiction Medicine Patient Placement Criteria (ASAM PPC) are guidelines for matching addiction patients to an optimal level of care (LOC). South Korea lacked a systematic approach to as...

    Authors: Jiyoung Hong, Seon-Hi Shin, Ji Eun Kim, Sang Kyu Lee, Hong Seok Oh, Euihyeon Na, Hyun Ji Cho and Sungwon Roh
    Citation: Addiction Science & Clinical Practice 2024 19:98
    Content type: Research Published on:

  46. Contingency management (CM), an incentive-based intervention to encourage target behaviors, effectively promotes medication adherence. However, efforts to extend CM to HIV pre-exposure prophylaxis (PrEP) have ...

    Authors: Eleanor Pickering, Adam Viera, Minhee L. Sung, Daniel Davidson, Genie Bailey, Marianne Buchelli, Mark Jenkins, Jennifer Kolakowski, Leah Maier, E. Jennifer Edelman and Carla J. Rash
    Citation: Addiction Science & Clinical Practice 2024 19:97
    Content type: Research Published on:

    • Primary care clinic structures and operations may influence early MOUD discontinuation.
    • Flexible scheduling can improve ear...

    Authors: Rebecca Arden Harris, Matthew Kearney, Shimrit Keddem, Tara Calderbank, Liza Tomczuk, Justin Clapp, Jeanmarie Perrone, Henry R. Kranzler, Judith A. Long and David S. Mandell
    Citation: Addiction Science & Clinical Practice 2024 19:96
    Content type: Research Published on:

  48. Receipt of medications for opioid use disorder (MOUD) critically reduces opioid-related mortality during the post-incarceration period. Optimal provision of this care to individuals on community supervision (i...

    Authors: Augustine W. Kang, Amelia Bailey, Anthony Surace, Lynda Stein, Damaris Rohsenow and Rosemarie A. Martin
    Citation: Addiction Science & Clinical Practice 2024 19:95
    Content type: Research Published on:

  50. Oral Pre-exposure prophylaxis (PrEP) is effective in preventing HIV transmission. However, despite high rates of HIV risk behaviors among people who inject drugs (PWID), this population remains underserved by ...

    Authors: Amaya Perez-Brumer, Rose Schmidt, Rebecca Kennedy, Jordan E. Lake, Yolanda R. Villarreal, Sydney Bornstein, Irene Kuo, Omar Nieto, Julie Franks, Cecile Denis, Nabila El-Bassel, Steve Shoptaw, Peter Davidson and Laramie R. Smith
    Citation: Addiction Science & Clinical Practice 2024 19:92
    Content type: Research Published on:
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Archival content

Addiction Science & Clinical Practice was formerly published by NIDA and previous issues of the journal can be viewed here.

Addiction Science & Clinical Practice

ISSN: 1940-0640